Channel blocker
A channel blocker (CB) or ion channel blocker (ICB) is a type of drug which binds inside the pore of a specific type of ion channel and blocks the flow of ions through it, resulting in an alteration of the electrochemical gradient of the cell membrane of neurons and therefore a change in neurotransmission.
Types of Channel Blockers
There are several different major classes of channel blockers, including:
The following types which act on ligand-gated ion channels (LGICs) via binding to their pore also exist:
These types of receptor antagonists are referred to as noncompetitive or uncompetitive.
See also
References
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Types |
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Classes |
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see Enzyme inhibition
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Miscellaneous
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Selective |
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Non-selective |
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Other/ungrouped |
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anat(a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot
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noco/syva/cong/lyvd/tumr, sysi/epon, injr
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proc, drug(C2s+n/3/4/5/7/8/9)
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